COMPARATIVE GENOMICS

All human beings or Homo Sapiens share 99.8% of their genome sequence and only 0.2% of the sequence varies between the different individuals. The variations in individual genomes are due to single nucleotides polymorphism or SNPs which can occur both in coding and non-coding regions of the genome. SNPs are DNA sequence variations which occur when a single base (A, C, G, or T) is altered so that different individuals may have different letters at these positions. These genomic variations determines the difference in our susceptibility to or protection from all kinds of diseases.